58 Best Startups in Manhattan to Watch in 2025

The Definitive Seedtable Ranking of Startups in Manhattan

We track 71,000+ companies and rank them dynamically using our Seedtable Score – a score that uses quantitative and qualitative data points to signal the momentum behind a company. We then monitor the list manually leveraging our expertise as founders and investors.

There are 58 start-ups with an aggregate funding of $5.0b. The average funding per company in this subset is $85.8m.

Last update to the database: Jul 15, 2025. See changelog.

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9

Funding Rounds

$2.5b

Money raised

Cockroachs Labs is the New York based company behind Cockroach DB, an open source, distributed SQL database.

4

Funding Rounds

$18.5m

Money raised

TripleLift is an American multinational technology company developing a platform that enables scalability for native, branded content and OTT advertising.

Location:

Key people:

4

Funding Rounds

$42.5m

Money raised

Vestwell is a Manhattan-based digital retirement platform providing turnkey solutions for financial advisors.

6

Funding Rounds

$230.6m

Money raised

Leader in delivering real-world evidence (RWE) and outcomes-based analytics solutions to life science companies and payers.

Key people:

3

Funding Rounds

$84.0m

Money raised

TytoCare is a healthcare delivery system with on-demand medical exams that can be done remotely.

1

Funding Rounds

An e-commerce company that sells high-quality hijabs with a focus on clientele in the United States. It was founded in 2010 and is located in New York City.

1

Funding Rounds

$12.0m

Money raised

Devron is focused on rethinking the way data science platforms read and share insights across datasets.

Location:

Key people:

3

Funding Rounds

$405.0m

Money raised

A company offering a platform for home owners to buy and sell property.

9

Funding Rounds

$219.8m

Money raised

Electric is a company founded in 2016 by Ryan Denehy.

1

Funding Rounds

$4.2m

Money raised

A company based in New York City providing a platform for guiding cyclist through safe and enjoyable bike routes.

Key people:

3

Funding Rounds

$110.0m

Money raised

Aquant is a New York-based software development company offering a service intelligence platform.

7

Funding Rounds

$86.3m

Money raised

Simulmedia is an advertisement company founded in 2009 Dave Morgan.

Key people:

4

Funding Rounds

$378.5m

Money raised

ASAPP is a developer of artificial intelligence and machine learning products for automation and human augmentation for customer experiences. The company was founded in 2014 by Marcus Westin and Gustavo Sapoznik.

5

Funding Rounds

$79.2m

Money raised

RippleMatch is a company founded in 2016 by Eric Ho.

Key people:

1

Funding Rounds

$10.0m

Money raised

Negotiatus is a company founded in 2016 by Tom Jaklitsch.

1

Funding Rounds

$1.0m

Money raised

Plug in a Neverware server and all of a school's old computers will run better than when they were new and will never need to be replaced again.

2

Funding Rounds

$7.1m

Money raised

Next-Gen Artificial Intelligence (AI) Company, based in New York.

Location:

Key people:

5

Funding Rounds

$22.0m

Money raised

Accrete automates analytical tasks to scale tacit knowledge and make accurate predictions about the real world.

Location:

Key people:

2

Funding Rounds

$8.7m

Money raised

Splacer, the 'Airbnb' of event spaces, is growing an online marketplace for people to list, discover, and book short-term event spaces.

Key people:

3

Funding Rounds

$27.0m

Money raised

Jumptuit provides an anticipatory alert & notification platform based on smart data analytics for a variety of industries.

3

Funding Rounds

$23.0m

Money raised

Fairygodboss offers career communities, career advice, job openings and company reviews geared toward women.

1

Funding Rounds

$1.5m

Money raised

Trusty.care is a company founded by Joseph Schneier.

Key people:

3

Funding Rounds

$115.0m

Money raised

The Wing is a company founded in 2016 by Lauren Kassan.

4

Funding Rounds

$66.0m

Money raised

Extend is an innovative digital credit card distribution platform that redefines how credit cards are issued and shared

Key people:

4

Funding Rounds

$11.9m

Money raised

Amperon is a company founded in 2017 by Abe Stanway.

Location:

Key people:

1

Funding Rounds

$1.7m

Money raised

Street Smarts offers specialized virtual reality simulated training experiences to prepare law enforcement & military for effective de-escalation of high stress situations

Location:

Key people:

2

Funding Rounds

$3.0m

Money raised

PivotDesk is a peer-to-peer company founded in 2012 by David Mandell.

1

Funding Rounds

$8.5m

Money raised

Castellum is a publicly traded defense-tech company specializing in cybersecurity, electronic warfare, and software systems for federal government clients. Headquartered in Bethesda, MD, and led by Glen Ives (CEO) with David Bell serving as CFO, the company has a workforce estimated between 26 and 260.

2

Funding Rounds

$22.0m

Money raised

Ezra AI is developing early cancer detection methods, using AI and MRI scanning.

4

Funding Rounds

$17.0m

Money raised

Taykey is a company founded in 2009 by Amit Avner.

Key people:

2

Funding Rounds

$6.3m

Money raised

Constrafor is a construction procurement company that offers financing and software for general contractors.

Location:

Key people:

1

Funding Rounds

$3.5m

Money raised

A company creating low cost exchange traded funds (ETFs).

Key people:

1

Funding Rounds

$2.5m

Money raised

Hash is a Manhattan-based company founded in 2019 by David Wilkinson.

Industries:

Location:

Key people:

1

Funding Rounds

$2.2m

Money raised

Minyanville is a Manhattan-based news company founded in 2002.

Industries:

Location:

1

Funding Rounds

$2.3m

Money raised

Cleanly is a company offering on-demand laundry delivery service.

2

Funding Rounds

$26.5m

Money raised

ShelterZoom is a technology company and the developer of a blockchain based real estate platform.

Key people:

1

Funding Rounds

$10.0m

Money raised

Firedome's tailormade solution for IoT companies is designed to proactively prevent, detect, and respond to inevitable vulnerabilities in connected devices.

1

Funding Rounds

$2.9m

Money raised

omniX labs is an artificial Intelligence company founded in 2018 by Muthla Al-Sayer.

1

Funding Rounds

$7.0m

Money raised

Link3D is a company founded in 2016 by Shane Fox.

1

Funding Rounds

$5.0k

Money raised

Fortis Biosciences is a biotechnology company that integrates human metabolomics and microbes research to improve the human immune system.

1

Funding Rounds

$3.0m

Money raised

Bakpax is an artificial Intelligence company founded in 2017 by Jose Ferreira, Will Fleiss and Trevor Summers Smith.

2

Funding Rounds

$7.0m

Money raised

Blueprint Power is a company founded by Robyn Beavers.

2

Funding Rounds

$750.0k

Money raised

Rockpapr is a company founded in 2018 by Aaron Wiernik.

Location:

Key people:

8

Funding Rounds

$201.8m

Money raised

Electric AI, Inc. is a company founded in 2016.

Location:

1

Funding Rounds

$12.0m

Money raised

FlexPoint is a modern payments platform purpose-built for the IT channel. They provide a modern checkout and accept a variety of payment options. They also provide white-label point-of-sale financing for large ticket invoices.

2

Funding Rounds

$27.5m

Money raised

Banza is a company founded in 2014.

Location:

1

Funding Rounds

$1.0m

Money raised

Hindsight Technology Solutions is a company founded in 2017 by Hersh Patel.

1

Funding Rounds

$3.5m

Money raised

eCaring is a Manhattan-based company.

1

Funding Rounds

$7.0m

Money raised

Instnt is a New York-based provider of a customer on-boarding platform.

Location:

Key people:

1

Funding Rounds

$1.3m

Money raised

Qineqt is a Manhattan-based company founded in 2013.

1

Funding Rounds

$15.0m

Money raised

Grailed is a Manhattan-based company founded by Arun Gupta.

Location:

Key people:

1

Funding Rounds

$2.5m

Money raised

Wine n Dine is a company founded in 2015.

1

Funding Rounds

$5.1m

Money raised

Cybera Global is a company founded in 2020.

1

Funding Rounds

$27.5m

Money raised

Tacombi is a restaurant company founded in 2005.

Industries:

1

Funding Rounds

OrthoSnap is a Manhattan-based company.

Industries:

Location:

2

Funding Rounds

$103.0m

Money raised

Vestwell Holdings Inc. is a financial technology company founded in 2016.

Industries:

Location:

1

Funding Rounds

$2.8m

Money raised

Location:

1

Funding Rounds

$3.0m

Money raised

Kid Made Modern is a company founded in 2012.

Location:

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